首页> 外文OA文献 >Acute effects of electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate in the cat: an evaluation of safety.
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Acute effects of electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate in the cat: an evaluation of safety.

机译:大脑电磁刺激对猫的皮层活动,皮层血流量,血压和心率的急性影响:安全性评估。

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摘要

The influence of repeated high intensity electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate has been investigated in the cat, to evaluate the safety of the method. The observations have been made in preparations under propofol anaesthesia before, during and after periods of anoxia. Electromagnetic stimulation of the brain evoked activity in descending motor pathways and was recorded by activity in the median nerve and by muscle twitches. Following repeated series of high intensity stimulation there were no systematic changes in somatosensory evoked potentials or background EEG, nor were there signs of epileptogenic activity during electromagnetic stimulation, before, during or after periods of anoxia. No systematic changes in cortical blood flow, blood pressure or heart rate were observed during electromagnetic stimulation, before or after periods of anoxia. In conclusion, no acute adverse consequences following electromagnetic stimulation in the normal and anoxic cat brain were demonstrated.
机译:在猫中研究了反复的高强度电磁刺激对大脑皮层活动,皮层血流量,血压和心率的影响,以评估该方法的安全性。在缺氧之前,期间和之后在异丙酚麻醉下的制剂中进行了观察。对大脑的电磁刺激在下降的运动路径中引起活动,并通过正中神经活动和肌肉抽搐来记录。在反复进行一系列高强度刺激后,体感诱发电位或本底脑电图没有系统性变化,在电磁刺激期间,缺氧之前,期间或之后也没有癫痫活动的迹象。在缺氧之前或之后的电磁刺激过程中,未观察到皮质血流量,血压或心率的系统变化。总之,在正常和缺氧的猫脑中,电磁刺激后均未发现急性不良后果。

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